设为首页  |  加入收藏  |  联系我们  |  English  |  中国科学院  
 首  页  实验室概况 研究队伍 科研工作 平台建设 开放交流 人才培养 规章制度
 
  当前位置:首页 > 最新论文  
Sequence of the Supernumerary B Chromosome of Maize Provides Insight into its Drive Mechanism and Evolution
 Nicolas Blavet, Hua Yang, Handong Su, Pavel Solansky, Ryan N. Douglas, Miroslava Karafiátová, Lucie Simková, Jing Zhang, Yalin Liu, Jie Hou, Xiaowen Shi, Chen Chen, Mohamed El-Walid, Morgan E. McCaw, Patrice S. Albert, Zhi Gao, Changzeng Zhao, Gil Ben-Zvi, Lior Glick, Guy Kol, Jinghua Shi, Jan Vrána, Hana Simková, Jonathan C. Lamb, Kathleen Newton, R. Kelly Dawe, Jaroslav Dolezel, Tieming Ji, Kobi Baruch, Jianlin Cheng, Fangpu Han, James A. Birchler, and Jan Bartos.


PNAS
DOI:10.1073/pnas.2104254118


Abstract

 

B chromosomes are enigmatic elements in thousands of plant and animal genomes that persist in populations despite being nonessential. They circumvent the laws of Mendelian inheritance but the molecular mechanisms underlying this behavior remain unknown. Here we present the sequence, annotation, and analysis of the maize B chromosome providing insight into its drive mechanism. The sequence assembly reveals detailed locations of the elements involved with the cis and trans functions of its drive mechanism, consisting of nondisjunction at the second pollen mitosis and preferential fertilization of the egg by the B-containing sperm. We identified 758 protein-coding genes in 125.9 Mb of B chromosome sequence, of which at least 88 are expressed. Our results demonstrate that transposable elements in the B chromosome are shared with the standard A chromosome set but multiple lines of evidence fail to detect a syntenic genic region in the A chromosomes, suggesting a distant origin. The current gene content is a result of continuous transfer from the A chromosomal complement over an extended evolutionary time with subsequent degradation but with selection for maintenance of this nonvital chromosome.
 
【打印本页】【关闭本页】
Copyright © 植物细胞与染色体工程国家重点实验室(中国科学院遗传与发育生物学研究所)
地址:北京市朝阳区北辰西路1号院2号 邮编:100101 电话: 010-64806537 传真: 010-64806537